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Inhibition of SENP5 suppresses cell growth and promotes apoptosis in osteosarcoma cells
SUMOylation is a dynamic and reversible process. Several SUMO-specific proteases (SENPs) that remove SUMO from substrates have been shown to be amplified in a subset of cancers. SENP5 is required for cell division, as well as maintaining mitochondrial morphology and function. SENP5 has been reported...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043617/ https://www.ncbi.nlm.nih.gov/pubmed/24926368 http://dx.doi.org/10.3892/etm.2014.1644 |