Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion

Motility of the protozoan parasite Toxoplasma gondii plays an important role in the parasite’s life cycle and virulence within animal and human hosts. Motility is driven by a myosin motor complex that is highly conserved across the Phylum Apicomplexa. Two key components of this complex are the class...

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Detalles Bibliográficos
Autores principales: Leung, Jacqueline M., Tran, Fanny, Pathak, Ravindra B., Poupart, Séverine, Heaslip, Aoife T., Ballif, Bryan A., Westwood, Nicholas J., Ward, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043638/
https://www.ncbi.nlm.nih.gov/pubmed/24892871
http://dx.doi.org/10.1371/journal.pone.0098056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043638/
https://www.ncbi.nlm.nih.gov/pubmed/24892871
http://dx.doi.org/10.1371/journal.pone.0098056

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