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Role of cytoskeletal proteins in cerebral cavernous malformation signaling pathways: a proteomic analysis

Three genetic mutations were found to cause cerebral cavernous malformation (CCM), a vascular anomaly predisposing affected individuals to hemorrhagic stroke. These CCM proteins function together as a protein complex in the cell. Loss of expression of each CCM gene results in loss of in vitro endoth...

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Detalles Bibliográficos
Autores principales: Baxter, Sarah Schwartz, Dibble, Christopher F., Byrd, Warren C., Carlson, Jim, Mack, Charles Russell, Saldarriaga, Ivandario, Bencharit, Sompop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043921/
https://www.ncbi.nlm.nih.gov/pubmed/24770493
http://dx.doi.org/10.1039/c3mb70199a