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Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes

Endoplasmic reticulum (ER) stress has been implicated in a variety of cardiovascular diseases. During ER stress, disruption of the complex of protein phosphatase 1 regulatory subunit 15A and catalytic subunit of protein phosphatase 1 by the small molecule guanabenz (antihypertensive, α(2)-adrenocept...

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Detalles Bibliográficos
Autores principales: Neuber, Christiane, Uebeler, June, Schulze, Thomas, Sotoud, Hannieh, El-Armouche, Ali, Eschenhagen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044035/
https://www.ncbi.nlm.nih.gov/pubmed/24892553
http://dx.doi.org/10.1371/journal.pone.0098893