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Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes
Endoplasmic reticulum (ER) stress has been implicated in a variety of cardiovascular diseases. During ER stress, disruption of the complex of protein phosphatase 1 regulatory subunit 15A and catalytic subunit of protein phosphatase 1 by the small molecule guanabenz (antihypertensive, α(2)-adrenocept...
Autores principales: | Neuber, Christiane, Uebeler, June, Schulze, Thomas, Sotoud, Hannieh, El-Armouche, Ali, Eschenhagen, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044035/ https://www.ncbi.nlm.nih.gov/pubmed/24892553 http://dx.doi.org/10.1371/journal.pone.0098893 |
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