Critical role of γ-phosphate in structural transition of Na,K-ATPase upon ATP binding

Active transport of sodium and potassium ions by Na,K-ATPase is accompanied by the enzyme conformational transition between E1 and E2 states. ATP and ADP bind to Na,K-ATPase in the E1 conformation with similar affinity but the properties of enzyme in complexes with these nucleotides are different. W...

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Detalles Bibliográficos
Autores principales: Petrushanko, Irina Yu., Mitkevich, Vladimir A., Anashkina, Anastasia A., Klimanova, Elizaveta A., Dergousova, Elena A., Lopina, Olga D., Makarov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044624/
https://www.ncbi.nlm.nih.gov/pubmed/24893715
http://dx.doi.org/10.1038/srep05165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044624/
https://www.ncbi.nlm.nih.gov/pubmed/24893715
http://dx.doi.org/10.1038/srep05165

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