Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

Direct in vivo administration of messenger RNA (mRNA) delivered in both naked and nanoparticle formats are actively investigated because the use of dendritic cells transfected ex vivo with mRNA for cancer therapy is expensive and needs significant infrastructure. Notably, intravenous and subcutaneou...

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Detalles Bibliográficos
Autores principales: Phua, Kyle K. L., Staats, Herman F., Leong, Kam W., Nair, Smita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044635/
https://www.ncbi.nlm.nih.gov/pubmed/24894817
http://dx.doi.org/10.1038/srep05128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044635/
https://www.ncbi.nlm.nih.gov/pubmed/24894817
http://dx.doi.org/10.1038/srep05128

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