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Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
Direct in vivo administration of messenger RNA (mRNA) delivered in both naked and nanoparticle formats are actively investigated because the use of dendritic cells transfected ex vivo with mRNA for cancer therapy is expensive and needs significant infrastructure. Notably, intravenous and subcutaneou...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044635/ https://www.ncbi.nlm.nih.gov/pubmed/24894817 http://dx.doi.org/10.1038/srep05128 |