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Tryps and trips: cell trafficking across the 100-year-old blood–brain barrier
One hundred years ago, Edwin E. Goldmann discovered the blood–brain barrier (BBB) using trypan dyes. These dyes were developed and named by Paul Ehrlich during his search for drugs to kill African trypanosomes (extracellular parasites that cause sleeping sickness) while sparing host cells. For Ehrli...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier Applied Science Publishing
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045197/ https://www.ncbi.nlm.nih.gov/pubmed/24780507 http://dx.doi.org/10.1016/j.tins.2014.03.007 |