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Tryps and trips: cell trafficking across the 100-year-old blood–brain barrier

One hundred years ago, Edwin E. Goldmann discovered the blood–brain barrier (BBB) using trypan dyes. These dyes were developed and named by Paul Ehrlich during his search for drugs to kill African trypanosomes (extracellular parasites that cause sleeping sickness) while sparing host cells. For Ehrli...

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Detalles Bibliográficos
Autores principales: Bentivoglio, Marina, Kristensson, Krister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Applied Science Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045197/
https://www.ncbi.nlm.nih.gov/pubmed/24780507
http://dx.doi.org/10.1016/j.tins.2014.03.007