Clinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers

BACKGROUND: MicroRNAs are associated with tumor genesis and progression in various carcinomas. MicroRNA-148a (miR-148a) was reported to have low expression in gastrointestinal cancers, and might be regulated by promoter region DNA methylation. METHODS: Bisulfite-modified sequencing was used to deter...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jingxu, Song, Yongxi, Wang, Zhenning, Wang, Guoli, Gao, Peng, Chen, Xiaowan, Gao, Zhaohua, Xu, Huimian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045258/
https://www.ncbi.nlm.nih.gov/pubmed/24920927
http://dx.doi.org/10.2147/OTT.S60888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045258/
https://www.ncbi.nlm.nih.gov/pubmed/24920927
http://dx.doi.org/10.2147/OTT.S60888

Ejemplares similares