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Clinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers

BACKGROUND: MicroRNAs are associated with tumor genesis and progression in various carcinomas. MicroRNA-148a (miR-148a) was reported to have low expression in gastrointestinal cancers, and might be regulated by promoter region DNA methylation. METHODS: Bisulfite-modified sequencing was used to deter...

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Detalles Bibliográficos
Autores principales:	Sun, Jingxu, Song, Yongxi, Wang, Zhenning, Wang, Guoli, Gao, Peng, Chen, Xiaowan, Gao, Zhaohua, Xu, Huimian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045258/ https://www.ncbi.nlm.nih.gov/pubmed/24920927 http://dx.doi.org/10.2147/OTT.S60888

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