Cargando…

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues

[Image: see text] The p300 and CBP transcriptional coactivator paralogs (p300/CBP) regulate a variety of different cellular pathways, in part, by acetylating histones and more than 70 non-histone protein substrates. Mutation, chromosomal translocation, or other aberrant activities of p300/CBP are li...

Descripción completa

Detalles Bibliográficos
Autores principales: Maksimoska, Jasna, Segura-Peña, Dario, Cole, Philip A., Marmorstein, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045318/
https://www.ncbi.nlm.nih.gov/pubmed/24819397
http://dx.doi.org/10.1021/bi500380f