Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model

Siglec-8 and siglec-F are paralogous membrane proteins expressed on human and murine eosinophils respectively. They bind similar sialylated and sulphated glycans and mediate eosinophil apoptosis when cross-linked with antibodies or glycan ligands. In models of allergic eosinophilic airway inflammati...

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Detalles Bibliográficos
Autores principales: McMillan, Sarah J., Richards, Hannah E., Crocker, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045373/
https://www.ncbi.nlm.nih.gov/pubmed/24698729
http://dx.doi.org/10.1016/j.imlet.2014.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045373/
https://www.ncbi.nlm.nih.gov/pubmed/24698729
http://dx.doi.org/10.1016/j.imlet.2014.03.008

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