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Synergistic Radioprotection by Gamma-Tocotrienol and Pentoxifylline: Role of cAMP Signaling

Purpose. This study was designed to determine the efficacy and mechanisms of radioprotection by the combination of gamma-tocotrienol (GT3) and pentoxifylline (PTX) against acute radiation injury. Materials and Methods. Post-irradiation survival was monitored to determine the most efficacious dose an...

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Detalles Bibliográficos
Autores principales: Kulkarni, Shilpa, Chakraborty, Kushal, Kumar, K. Sree, Kao, Tzu-Cheg, Hauer-Jensen, Martin, Ghosh, Sanchita P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045513/
https://www.ncbi.nlm.nih.gov/pubmed/24959559
http://dx.doi.org/10.5402/2013/390379