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Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is a highly diverse group that is associated with an aggressive phenotype. Its treatment has been challenging due to its heterogeneity and absence of well-defined molecular targets. Thus, there is an urgent need to identify novel agents with therapeut...

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Detalles Bibliográficos
Autores principales: Arora, Ritu, Yates, Clayton, Gary, Bernard D., McClellan, Steven, Tan, Ming, Xi, Yaguang, Reed, Eddie, Piazza, Gary A., Owen, Laurie B., Dean-Colomb, Windy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045585/
https://www.ncbi.nlm.nih.gov/pubmed/24896091
http://dx.doi.org/10.1371/journal.pone.0098370