Excess congenital non-synonymous variation in leukemia-associated genes in MLL− infant leukemia: a Children's Oncology Group report

Infant leukemia (IL) is a rare sporadic cancer with a grim prognosis. Although most cases are accompanied by MLL rearrangements and harbor very few somatic mutations, less is known about the genetics of the cases without MLL translocations. We performed the largest exome-sequencing study to date on...

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Detalles Bibliográficos
Autores principales: Valentine, M C, Linabery, A M, Chasnoff, S, Hughes, A E O, Mallaney, C, Sanchez, N, Giacalone, J, Heerema, N A, Hilden, J M, Spector, L G, Ross, J A, Druley, T E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045651/
https://www.ncbi.nlm.nih.gov/pubmed/24301523
http://dx.doi.org/10.1038/leu.2013.367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045651/
https://www.ncbi.nlm.nih.gov/pubmed/24301523
http://dx.doi.org/10.1038/leu.2013.367

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