Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments

Iron Regulatory Protein 2 (Irp2, Ireb2) is a central regulator of cellular iron homeostasis in vertebrates. Two global knockout mouse models have been generated to explore the role of Irp2 in regulating iron metabolism. While both mouse models show that loss of Irp2 results in microcytic anemia and...

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Detalles Bibliográficos
Autores principales: Zumbrennen-Bullough, Kimberly B., Becker, Lore, Garrett, Lillian, Hölter, Sabine M., Calzada-Wack, Julia, Mossbrugger, Ilona, Quintanilla-Fend, Leticia, Racz, Ildiko, Rathkolb, Birgit, Klopstock, Thomas, Wurst, Wolfgang, Zimmer, Andreas, Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabě, Romney, Steven J., Leibold, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045679/
https://www.ncbi.nlm.nih.gov/pubmed/24896637
http://dx.doi.org/10.1371/journal.pone.0098072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045679/
https://www.ncbi.nlm.nih.gov/pubmed/24896637
http://dx.doi.org/10.1371/journal.pone.0098072

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