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Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema after Tissue Plasminogen Activator Treatment for Ischemic Stroke in Rats

An angiogenesis factor, angiopoietin-1 (Ang1), is associated with the blood-brain barrier (BBB) disruption after focal cerebral ischemia. However, whether hemorrhagic transformation and cerebral edema after tissue plasminogen activator (tPA) treatment are related to the decrease in Ang1 expression i...

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Detalles Bibliográficos
Autores principales: Kawamura, Kunio, Takahashi, Tetsuya, Kanazawa, Masato, Igarashi, Hironaka, Nakada, Tsutomu, Nishizawa, Masatoyo, Shimohata, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045756/
https://www.ncbi.nlm.nih.gov/pubmed/24896569
http://dx.doi.org/10.1371/journal.pone.0098639