Catalytic Activity of cGMP-Dependent Protein Kinase Type I in Intact Cells Is Independent of N-Terminal Autophosphorylation

Although cGMP-dependent protein kinase type I (cGKI) is an important mediator of cGMP signaling and upcoming drug target, its in vivo-biochemistry is not well understood. Many studies showed that purified cGKI autophosphorylates multiple sites at its N-terminus. Autophosphorylation might be involved...

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Detalles Bibliográficos
Autores principales: Vallur, Raghavan, Kalbacher, Hubert, Feil, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045857/
https://www.ncbi.nlm.nih.gov/pubmed/24897423
http://dx.doi.org/10.1371/journal.pone.0098946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045857/
https://www.ncbi.nlm.nih.gov/pubmed/24897423
http://dx.doi.org/10.1371/journal.pone.0098946

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