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Investigation of HOXA9 promoter methylation as a biomarker to distinguish oral cancer patients at low risk of neck metastasis

BACKGROUND: Metastasis to the cervical (neck) lymph nodes is one of the most significant clinical factors responsible for death from oral squamous cell carcinoma (SCC). Therefore, the lymph nodes are frequently removed when the tumor is excised (neck dissection), even though the majority of patients...

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Detalles Bibliográficos
Autores principales: Uchida, Kenichiro, Veeramachaneni, Ratna, Huey, Bing, Bhattacharya, Aditi, Schmidt, Brian L, Albertson, Donna G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045880/
https://www.ncbi.nlm.nih.gov/pubmed/24886209
http://dx.doi.org/10.1186/1471-2407-14-353