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Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity

BACKGROUND: Protein phosphates 4 (PP4), encoded by the ppp4c gene, is a ubiquitously expressed phosphatase that has been implicated in the regulation of cytokine signaling and lymphocyte survival; recent reports suggest that PP4 may be involved in pre-TCR signaling and B cell development. However, w...

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Detalles Bibliográficos
Autores principales: Liao, Fang-Hsuean, Shui, Jr-Wen, Hsing, En-Wei, Hsiao, Wan-Yi, Lin, Yu-Chun, Chan, Yi-Chiao, Tan, Tse-Hua, Huang, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045899/
https://www.ncbi.nlm.nih.gov/pubmed/24904742
http://dx.doi.org/10.1186/2045-3701-4-25