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Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

BACKGROUND: Consecutive treatment of normal heart with a high dose of isoproterenol and adenosine (Iso/Ade treatment), confers strong protection against ischaemia/reperfusion injury. In preparation for translation of this cardioprotective strategy into clinical practice during heart surgery, we furt...

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Detalles Bibliográficos
Autores principales: Khaliulin, Igor, Halestrap, Andrew P, Bryant, Simon M, Dudley, Declan J, James, Andrew F, Suleiman, M-Saadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045901/
https://www.ncbi.nlm.nih.gov/pubmed/24885907
http://dx.doi.org/10.1186/1479-5876-12-139