Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

Rare inherited cardiovascular diseases are frequently caused by mutations in genes that are essential for the formation and/or function of the cardiovasculature. Hereditary Haemorrhagic Telangiectasia is a familial disease of this type. The majority of patients carry mutations in either Endoglin (EN...

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Detalles Bibliográficos
Autores principales: Tual-Chalot, Simon, Mahmoud, Marwa, Allinson, Kathleen R., Redgrave, Rachael E., Zhai, Zhenhua, Oh, S. Paul, Fruttiger, Marcus, Arthur, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045906/
https://www.ncbi.nlm.nih.gov/pubmed/24896812
http://dx.doi.org/10.1371/journal.pone.0098646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045906/
https://www.ncbi.nlm.nih.gov/pubmed/24896812
http://dx.doi.org/10.1371/journal.pone.0098646

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