CDK9 inhibition strategy defines distinct sets of target genes

BACKGROUND: CDK9 is the catalytic subunit of the Positive Transcription Elongation Factor b (P-TEFb), which phosphorylates the CTD of RNAPII and negative elongation factors enabling for productive elongation after initiation. CDK9 associates with T-type cyclins and cyclin K and its activity is tight...

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Detalles Bibliográficos
Autores principales: Garriga, Judit, Graña, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045923/
https://www.ncbi.nlm.nih.gov/pubmed/24886624
http://dx.doi.org/10.1186/1756-0500-7-301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045923/
https://www.ncbi.nlm.nih.gov/pubmed/24886624
http://dx.doi.org/10.1186/1756-0500-7-301

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