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CD8+ TCR Transgenic Strains Expressing Public versus Private TCR Targeting the Respiratory Syncytial Virus K(d)M2(82–90) Epitope Demonstrate Similar Functional Profiles

Our previous work has characterized the functional and clonotypic features of two respiratory syncytial virus (RSV) epitope-specific T cell responses in mice. Following single-cell sequencing, we selected T cell receptor sequences to represent both a public and a private clone specific for the domin...

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Detalles Bibliográficos
Autores principales: Bar-Haim, Erez, Erez, Noam, Malloy, Allison M. W., Graham, Barney S., Ruckwardt, Tracy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045939/
https://www.ncbi.nlm.nih.gov/pubmed/24897427
http://dx.doi.org/10.1371/journal.pone.0099249