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Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
AIM: Chemotherapy with doxorubicin is limited by cardiotoxicity. Free radical generation and mitochondrial dysfunction are thought to contribute to doxorubicin-induced cardiac failure. In this study we wanted to investigate if opening of mitochondrial K(ATP)-channels by diazoxide is protective again...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045949/ https://www.ncbi.nlm.nih.gov/pubmed/24887454 http://dx.doi.org/10.1186/2050-6511-15-28 |