Selective and flexible depletion of problematic sequences from RNA-seq libraries at the cDNA stage

BACKGROUND: A major hurdle to transcriptome profiling by deep-sequencing technologies is that abundant transcripts, such as rRNAs, can overwhelm the libraries, severely reducing transcriptome-wide coverage. Methods for depletion of such unwanted sequences typically require treatment of RNA samples p...

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Detalles Bibliográficos
Autores principales: Archer, Stuart K, Shirokikh, Nikolay E, Preiss, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045971/
https://www.ncbi.nlm.nih.gov/pubmed/24886553
http://dx.doi.org/10.1186/1471-2164-15-401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045971/
https://www.ncbi.nlm.nih.gov/pubmed/24886553
http://dx.doi.org/10.1186/1471-2164-15-401

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