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TIP peptide inhalation in experimental acute lung injury: effect of repetitive dosage and different synthetic variants

BACKGROUND: Inhalation of TIP peptides that mimic the lectin-like domain of TNF-α is a novel approach to attenuate pulmonary oedema on the threshold to clinical application. A placebo-controlled porcine model of acute respiratory distress syndrome (ARDS) demonstrated a reduced thermodilution-derived...

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Detalles Bibliográficos
Autores principales: Hartmann, Erik K, Thomas, Rainer, Liu, Tanghua, Stefaniak, Joanna, Ziebart, Alexander, Duenges, Bastian, Eckle, Daniel, Markstaller, Klaus, David, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046002/
https://www.ncbi.nlm.nih.gov/pubmed/24904234
http://dx.doi.org/10.1186/1471-2253-14-42