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TIP peptide inhalation in experimental acute lung injury: effect of repetitive dosage and different synthetic variants
BACKGROUND: Inhalation of TIP peptides that mimic the lectin-like domain of TNF-α is a novel approach to attenuate pulmonary oedema on the threshold to clinical application. A placebo-controlled porcine model of acute respiratory distress syndrome (ARDS) demonstrated a reduced thermodilution-derived...
Autores principales: | Hartmann, Erik K, Thomas, Rainer, Liu, Tanghua, Stefaniak, Joanna, Ziebart, Alexander, Duenges, Bastian, Eckle, Daniel, Markstaller, Klaus, David, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046002/ https://www.ncbi.nlm.nih.gov/pubmed/24904234 http://dx.doi.org/10.1186/1471-2253-14-42 |
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