A human sleep homeostasis phenotype in mice expressing a primate-specific PER3 variable-number tandem-repeat coding-region polymorphism

In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...

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Detalles Bibliográficos
Autores principales: Hasan, Sibah, van der Veen, Daan R., Winsky-Sommerer, Raphaelle, Hogben, Alexandra, Laing, Emma E., Koentgen, Frank, Dijk, Derk-Jan, Archer, Simon N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2014
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046067/
https://www.ncbi.nlm.nih.gov/pubmed/24577121
http://dx.doi.org/10.1096/fj.13-240135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046067/
https://www.ncbi.nlm.nih.gov/pubmed/24577121
http://dx.doi.org/10.1096/fj.13-240135

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