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A human sleep homeostasis phenotype in mice expressing a primate-specific PER3 variable-number tandem-repeat coding-region polymorphism
In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...
Autores principales: | Hasan, Sibah, van der Veen, Daan R., Winsky-Sommerer, Raphaelle, Hogben, Alexandra, Laing, Emma E., Koentgen, Frank, Dijk, Derk-Jan, Archer, Simon N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046067/ https://www.ncbi.nlm.nih.gov/pubmed/24577121 http://dx.doi.org/10.1096/fj.13-240135 |
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