Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala

Recently discovered neuropeptide S (NPS) has anxiolytic and pain-inhibiting effects in rodents. We showed previously that NPS increases synaptic inhibition of amygdala output to inhibit pain behaviors. The amygdala plays a key role in emotional-affective aspects of pain. Of clinical significance is...

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Detalles Bibliográficos
Autores principales: Medina, Georgina, Ji, Guangchen, Grégoire, Stéphanie, Neugebauer, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046088/
https://www.ncbi.nlm.nih.gov/pubmed/24884567
http://dx.doi.org/10.1186/1744-8069-10-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046088/
https://www.ncbi.nlm.nih.gov/pubmed/24884567
http://dx.doi.org/10.1186/1744-8069-10-32

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