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Population pharmacokinetics of mefloquine, administered as a fixed-dose combination of artesunate-mefloquine in Indian patients for the treatment of acute uncomplicated Plasmodium falciparum malaria

BACKGROUND: Fixed-dose combinations of artemisinin combination therapy are strongly recommended to facilitate drug administration and compliance. New fixed-dose combinations must nevertheless be evaluated in relevant populations in terms of efficacy and pharmacokinetics. METHODS: A single-arm, open-...

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Detalles Bibliográficos
Autores principales: Jullien, Vincent, Valecha, Neena, Srivastava, Bina, Sharma, Bhawna, Kiechel, Jean-René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046089/
https://www.ncbi.nlm.nih.gov/pubmed/24886117
http://dx.doi.org/10.1186/1475-2875-13-187