Direct Observation of the Three Regions in α-Synuclein that Determine its Membrane-Bound Behaviour

α-synuclein (αS) is a protein involved in neurotransmitter release in presynaptic terminals, and whose aberrant aggregation is associated with Parkinson’s disease. In dopaminergic neurons, αS exists in a tightly regulated equilibrium between water-soluble and membrane-associated forms. Here we used...

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Detalles Bibliográficos
Autores principales: Fusco, Giuliana, De Simone, Alfonso, Tata, Gopinath, Vostrikov, Vitaly, Vendruscolo, Michele, Dobson, Christopher M., Veglia, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046108/
https://www.ncbi.nlm.nih.gov/pubmed/24871041
http://dx.doi.org/10.1038/ncomms4827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046108/
https://www.ncbi.nlm.nih.gov/pubmed/24871041
http://dx.doi.org/10.1038/ncomms4827

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