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eIF2B is a decameric guanine nucleotide exchange factor with a γ(2)ε(2) tetrameric core

eIF2B facilitates and controls protein synthesis in eukaryotes by mediating guanine nucleotide exchange on its partner eIF2. We combined mass spectrometry (MS) with chemical cross-linking, surface accessibility measurements and homology modelling to define subunit stoichiometry and interactions with...

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Detalles Bibliográficos
Autores principales:	Gordiyenko, Yuliya, Schmidt, Carla, Jennings, Martin D., Matak-Vinkovic, Dijana, Pavitt, Graham D., Robinson, Carol V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046112/ https://www.ncbi.nlm.nih.gov/pubmed/24852487 http://dx.doi.org/10.1038/ncomms4902

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