Nutlin-3 overcomes arsenic trioxide resistance and tumor metastasis mediated by mutant p53 in Hepatocellular Carcinoma

BACKGROUND: Arsenic trioxide has been demonstrated as an effective anti-cancer drug against leukemia and solid tumors both in vitro and in vivo. However, recent phase II trials demonstrated that single agent arsenic trioxide was poorly effective against hepatocellular carcinoma (HCC), which might be...

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Detalles Bibliográficos
Autores principales: Zheng, Tongsen, Yin, Dalong, Lu, Zhaoyang, Wang, Jiabei, Li, Yuejin, Chen, Xi, Liang, Yingjian, Song, Xuan, Qi, Shuyi, Sun, Boshi, Xie, Changming, Meng, Xianzhi, Pan, Shangha, Liu, Jiaren, Jiang, Hongchi, Liu, Lianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046148/
https://www.ncbi.nlm.nih.gov/pubmed/24884809
http://dx.doi.org/10.1186/1476-4598-13-133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046148/
https://www.ncbi.nlm.nih.gov/pubmed/24884809
http://dx.doi.org/10.1186/1476-4598-13-133

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