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Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii

BACKGROUND: Lacking enzymes for sterol synthesis, the intracellular protozoan Toxoplasma gondii scavenges cholesterol from host cells to multiply. T. gondii has a complex life cycle consisting of two asexual stages; the proliferative stage (tachyzoite), and the latent stage characterized by tissue c...

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Detalles Bibliográficos
Autores principales: Ihara, Fumiaki, Nishikawa, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046157/
https://www.ncbi.nlm.nih.gov/pubmed/24885547
http://dx.doi.org/10.1186/1756-3305-7-248