Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction

Mitogen-activated protein kinases (MAPKs) are involved in the regulation of cardiac hypertrophy and myocyte survival. Extracellular signal regulated protein kinase 1 and 2 (ERK1/2) are key components in the MAPK signaling pathways. Dysfunction of ERK1/2 in congenital heart diseases (Noonan syndrome...

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Detalles Bibliográficos
Autores principales: Ulm, Susanne, Liu, Wei, Zi, Min, Tsui, Hoyee, Chowdhury, Sanjoy K., Endo, Shogo, Satoh, Yasushi, Prehar, Sukhpal, Wang, Ruoxi, Cartwright, Elizabeth J., Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046245/
https://www.ncbi.nlm.nih.gov/pubmed/24631771
http://dx.doi.org/10.1016/j.yjmcc.2014.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046245/
https://www.ncbi.nlm.nih.gov/pubmed/24631771
http://dx.doi.org/10.1016/j.yjmcc.2014.03.002

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