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Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action

BACKGROUND: Occludin, a tight junction protein, plays an important role in maintaining the integrity of the lung epithelial barrier; however, its role in ventilation-induced lung injury has not been explored. Here, we measured the expression of occludin with different tidal volumes. Our study indica...

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Detalles Bibliográficos
Autores principales: Liu, Mengjie, Gu, Changping, Wang, Yuelan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046497/
https://www.ncbi.nlm.nih.gov/pubmed/24884662
http://dx.doi.org/10.1186/1471-2466-14-94