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The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

BACKGROUND: Traditional diagnoses of major depressive disorder (MDD) suggested that the presence or absence of stress prior to onset results in either ‘reactive’ or ‘endogenous’ subtypes of the disorder, respectively. Several lines of research suggest that the biological underpinnings of ‘reactive’...

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Detalles Bibliográficos
Autores principales: Malki, Karim, Keers, Robert, Tosto, Maria Grazia, Lourdusamy, Anbarasu, Carboni, Lucia, Domenici, Enrico, Uher, Rudolf, McGuffin, Peter, Schalkwyk, Leonard C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046519/
https://www.ncbi.nlm.nih.gov/pubmed/24886127
http://dx.doi.org/10.1186/1741-7015-12-73