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In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer

BACKGROUND: Inflammation increases the risk of colorectal cancer (CRC). We and others have described a role for TLR4, the receptor for LPS, in colon cancer. To explore the relationships between TLR4 expression and CRC, we combined the strength of transcriptome array data and immunohistochemical (IHC...

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Detalles Bibliográficos
Autores principales: Sussman, Daniel A, Santaolalla, Rebeca, Bejarano, Pablo A, Garcia-Buitrago, Monica T, Perez, Maria T, Abreu, Maria T, Clarke, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046523/
https://www.ncbi.nlm.nih.gov/pubmed/24887394
http://dx.doi.org/10.1186/1756-9966-33-45