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Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance

Fluctuations in organelle abundance can profoundly limit the precision of cell biological processes from secretion to metabolism. We modeled the dynamics of organelle biogenesis and predicted that organelle abundance fluctuations depend strongly on the specific mechanisms that increase or decrease t...

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Detalles Bibliográficos
Autores principales: Mukherji, Shankar, O'Shea, Erin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046565/
https://www.ncbi.nlm.nih.gov/pubmed/24916159
http://dx.doi.org/10.7554/eLife.02678