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Translational profiling in childhood acute lymphoblastic leukemia: no evidence for glucocorticoid regulation of mRNA translation

BACKGROUND: Glucocorticoids (GCs) are natural stress induced steroid hormones causing cell cycle arrest and cell death in lymphoid tissues. Therefore they are the central component in the treatment of lymphoid malignancies, in particular childhood acute lymphoblastic leukemia (chALL). GCs act mainly...

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Detalles Bibliográficos
Autores principales: Aneichyk, Tatsiana, Bindreither, Daniel, Mantinger, Christine, Grazio, Daniela, Goetsch, Katrin, Kofler, Reinhard, Rainer, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046653/
https://www.ncbi.nlm.nih.gov/pubmed/24289529
http://dx.doi.org/10.1186/1471-2164-14-844