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Brains from non-Alzheimer’s individuals containing amyloid deposits accelerate Aβ deposition in vivo

BACKGROUND: One of the main features of Alzheimer’s disease (AD) is the presence of Aβ deposits, which accumulate in the brain years before the onset of symptoms. We and others have demonstrated that cerebral Aβ-amyloidosis can be induced in vivo by administration of AD-brain extracts into transgeni...

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Detalles Bibliográficos
Autores principales: Duran-Aniotz, Claudia, Morales, Rodrigo, Moreno-Gonzalez, Ines, Hu, Ping Ping, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046659/
https://www.ncbi.nlm.nih.gov/pubmed/24252208
http://dx.doi.org/10.1186/2051-5960-1-76