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Supervised categorical principal component analysis for genome-wide association analyses

In order to have a better understanding of unexplained heritability for complex diseases in conventional Genome-Wide Association Studies (GWAS), aggregated association analyses based on predefined functional regions, such as genes and pathways, become popular recently as they enable evaluating joint...

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Detalles Bibliográficos
Autores principales: Lu, Meng, Lee, Hye-Seung, Hadley, David, Huang, Jianhua Z, Qian, Xiaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046680/
https://www.ncbi.nlm.nih.gov/pubmed/24564304
http://dx.doi.org/10.1186/1471-2164-15-S1-S10