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Towards sequence-based prediction of mutation-induced stability changes in unseen non-homologous proteins
BACKGROUND: Reliable prediction of stability changes induced by a single amino acid substitution is an important aspect of computational protein design. Several machine learning methods capable of predicting stability changes from the protein sequence alone have been introduced. Prediction performan...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046685/ https://www.ncbi.nlm.nih.gov/pubmed/24564514 http://dx.doi.org/10.1186/1471-2164-15-S1-S4 |