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Towards sequence-based prediction of mutation-induced stability changes in unseen non-homologous proteins

BACKGROUND: Reliable prediction of stability changes induced by a single amino acid substitution is an important aspect of computational protein design. Several machine learning methods capable of predicting stability changes from the protein sequence alone have been introduced. Prediction performan...

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Detalles Bibliográficos
Autores principales:	Folkman, Lukas, Stantic, Bela, Sattar, Abdul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046685/ https://www.ncbi.nlm.nih.gov/pubmed/24564514 http://dx.doi.org/10.1186/1471-2164-15-S1-S4

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