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Characterising ChIP-seq binding patterns by model-based peak shape deconvolution

BACKGROUND: Chromatin immunoprecipitation combined with massive parallel sequencing (ChIP-seq) is widely used to study protein-chromatin interactions or chromatin modifications at genome-wide level. Sequence reads that accumulate locally at the genome (peaks) reveal loci of selectively modified chro...

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Detalles Bibliográficos
Autores principales: Mendoza-Parra, Marco-Antonio, Nowicka, Malgorzata, Van Gool, Wouter, Gronemeyer, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046686/
https://www.ncbi.nlm.nih.gov/pubmed/24279297
http://dx.doi.org/10.1186/1471-2164-14-834