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Characterising ChIP-seq binding patterns by model-based peak shape deconvolution
BACKGROUND: Chromatin immunoprecipitation combined with massive parallel sequencing (ChIP-seq) is widely used to study protein-chromatin interactions or chromatin modifications at genome-wide level. Sequence reads that accumulate locally at the genome (peaks) reveal loci of selectively modified chro...
| Autores principales: | , , , |
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| 格式: | Online Artículo Texto |
| 語言: | English |
| 出版: |
BioMed Central
2013
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| 主題: | |
| 在線閱讀: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046686/ https://www.ncbi.nlm.nih.gov/pubmed/24279297 http://dx.doi.org/10.1186/1471-2164-14-834 |