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Accumulation of CTCF-binding sites drives expression divergence between tandemly duplicated genes in humans
BACKGROUND: During eukaryotic genome evolution, tandem gene duplication is the most frequent event giving rise to clustered gene families. However, how expression divergence between tandemly duplicated genes has emerged and maintained remain unclear. In particular, it is unknown if epigenetic regula...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046690/ https://www.ncbi.nlm.nih.gov/pubmed/24564680 http://dx.doi.org/10.1186/1471-2164-15-S1-S8 |