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Accumulation of CTCF-binding sites drives expression divergence between tandemly duplicated genes in humans

BACKGROUND: During eukaryotic genome evolution, tandem gene duplication is the most frequent event giving rise to clustered gene families. However, how expression divergence between tandemly duplicated genes has emerged and maintained remain unclear. In particular, it is unknown if epigenetic regula...

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Detalles Bibliográficos
Autores principales: Liao, Ben-Yang, Chang, Andrew Ying-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046690/
https://www.ncbi.nlm.nih.gov/pubmed/24564680
http://dx.doi.org/10.1186/1471-2164-15-S1-S8